While humans can escape the heat by seeking shade or shedding layers, plants remain rooted in place. So how do they survive ...

The results have appeared under the title 'Xrp1 governs the stress response program to spliceosome dysfunction' in Nucleic Acids Research. All eukaryotes (i.e. organisms in which DNA is enclosed ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing ...

The Galej Group at EMBL Grenoble has recently published new structural insights into minor spliceosome function in the journal Molecular Cell. Read the full story here .

Intron removal requires assembly of the spliceosome on precursor mRNA (pre-mRNA) and extensive remodelling to form the spliceosome’s catalytic centre. Here we report the cryo-electron microscopy ...

Romancing the Spliceosome to Fight Spinal Muscular Atrophy. ... such as stress or cellular injury. 2,3 Identifying small molecules that modify splicing and in turn alter the quantity or ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing ...