Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...

So the cells are able to "read" the instructions for building proteins stored in these genetic mosaic particles, they are first copied into precursors of mRNA, or messenger RNA. The spliceosome ...

How does the cell select this information? A large molecular machine called the spliceosome continuously separates the coding and non-coding regions of our genes—and it's doing this even as you ...

MYB acts as a master regulator of cell proliferation ... design small-molecule glues to modulate the interactions among the spliceosome, regulatory proteins, and RNAs. Our lead programs and ...

For organs to develop, grow and regenerate, cells must proliferate. But when that process goes awry, leading to uncontrolled cell growth, cancer can emerge.

The fit between a splice site and the spliceosome components that bind it influences splicing ... is a process closely linked to alternative splicing that allows cells to control protein production. 1 ...

Rgenta Therapeutics, a clinical-stage biotechnology company pioneering the development of a new class of oral small molecules ...