ES019 targets two checkpoint inhibitors – PD-L1 and SIRP-alpha – that work in different ways to boost immune responses against cancers. Targeting SIRP-alpha primes macrophages to attack and ...
OSE-172 blocks the SIRP-alpha myeloid-cell inhibitory receptor, and a spokesperson said that based on pre-clinical data there is a “strong rationale” for a combination therapy involving the ...
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