Discovery identifies a highly efficient human reverse transcriptase that can write RNA sequences into DNA. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2021 / 06 ...

More information: Kaiyang Zheng et al, Diversity of reverse-transcriptase-containing viruses through global metagenomics, ...

Indeed, the discovery of reverse transcriptase had a significant effect on the management and treatment of HIV infections, including Acquired Immunodeficiency Syndrome (AIDS), in the 1980s.

The genetic encephalopathy Aicardi–Goutières syndrome is thought to be due to misidentification of self-derived nucleic acids and the induction of a type I interferon–mediated response.

The global reverse transcriptase enzymes market is on track for significant expansion, driven by their essential role in molecular biology and increasing demand across various sectors. According to ...

For example, reverse transcriptase is the enzyme in HIV that is responsible for converting an RNA template into DNA. Highly active antiretroviral therapy (HAART): This combination treatment includes ...

They do this by blocking an enzyme called reverse transcriptase that helps HIV make copies of itself. There are several FDA-approved NRTIs. They include: Abacavir ...

WarmStart RTx is an in silico-engineered thermostable reverse transcriptase, designed by our researchers for speed, sensitivity and inhibitor resistance in reverse transcription loop-mediated ...

Sequence variations in human immunodeficiency virus (HIV)-1 reverse transcriptase (RT) and protease, the molecular targets of anti-retroviral drug therapy, are prime examples of genes in which ...

Results from using RNAscope technology to detect novel truncated RNAs in the aging human brain created by the "jumping" of long interspersed nuclear element-1, a genetic sequence known to use its ...

HIV reverse transcriptase inhibitors are the backbone of HAART. This article reviews current knowledge on drug-resistance HIV RT mutations, their molecular mechanisms, and clinical significance.

Telomerase reverse transcriptase (TERT) is expressed constitutively in tumour cells throughout the evolution of many cancers; therefore, this potential tumour self-antigen has been an important ...