Nature4y
DNA Transcription
The RNA strand is then cleaved by a complex that appears to associate with the polymerase. Cleavage seems to be coupled with termination of transcription and occurs at a consensus sequence.
EurekAlert!1y
ARS2 instructs early transcription termination-coupled RNA decay by recruiting ZC3H4 to nascent transcripts. (IMAGE)
where it induces transcription termination. NEXT is then recruited through a direct interaction between ZCCHC8 and ZC3H4, which lead to RNA degradation by the RNA exosome ...
EMBO Press6d
Induction of a transcriptional adaptation response by RNA destabilization events
This study shows that RNA decay rather than the presence of premature termination codons triggers a TA-like response.
CU Boulder News & Events1y
Understanding mechanisms that regulate transcription genome-wide as cells respond to stress
mRNA transcription by RNA polymerase II (Pol II ... Most recently we have focused our studies on how the termination of mRNA transcription is altered by heat shock. In the past several years, several ...
Hosted on MSN2mon
Novel mechanism eliminates 'bad' enzyme during gene expression
The process of transcription elongation by RNA polymerase II (Pol II), in which ... lost and forces Pol II to enter a "noncanonical early termination pathway," in which Pol II is ultimately ...
Research provides new insights into role of mechanical forces in gene expression
Transcription is the process by which a cell makes an RNA copy of a segment of DNA ... The canonical view of termination ...