Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

Cambridge, Massachusetts-based Envisagenics focuses on using AI to analyse errors in RNA splicing, a process in which a precursor form of messenger RNA (mRNA) – which is used as a template for ...

Then the RNA binding protein communicates to the splicing ... At the posttranscriptional level, nonsense mediated decay (NMD) is a process closely linked to alternative splicing that allows cells to ...

Christine Guthrie, a molecular geneticist whose studies of eukaryotic RNA yielded crucial insights into the workings of pre-mRNA splicing, the process by which introns are removed to produce mature ...

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Alternative splicing (AS), a critical process for gene expression regulation, allows a single precursor ...

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...