To explore whether the elongation of RNA, achieved by linking individual RNA units together, is regulated allosterically, the researchers altered the structure of the R3C ligase. They did this by ...

This process is called elongation. Three of the four nitrogenous bases that make up RNA — adenine (A), cytosine (C), and guanine (G) — are also found in DNA. In RNA, however, a base called ...

Ribosomes undergo changes in conformational state, striking different, well-orchestrated poses that allow strands of RNA to be fed through ... a process called elongation. Using HRTM, the ...

Our mission is to elucidate fundamental mechanisms that control the elongation phase of transcription by RNA polymerase II (Pol II) in normal and disease states. We are particularly interested in ...