The Galej Group at EMBL Grenoble has published new structural insights into minor spliceosome function in the journal Molecular Cell.

Enhancing protein diversity and guiding cellular functions, alternative splicing is a key dimension of genetic regulation.

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing ...

After a decade of work, scientists have completed a molecular model of the human spliceosome, an incredibly complex cellular machine. When an active gene is expressed in a cell, it is transcribed into ...

Researchers have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine in human biology. The vast majority of human genes -- more than nine in ten ...

The spliceosome does the genetic cutting and pasting. It is a complicated complex, made up of four major parts and more than 100 accessory proteins that come together and break apart throughout ...

Researchers have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine inside every cell.

The spliceosome in the spotlight «With a very long and truly complex computer simulation, working on a model originating from yeast, we have been able to shed light on the core of the spliceosome.