Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...

The spliceosome then converts them into mature, functional mRNA. To do this, this large protein-RNA complex, which is located in the cell nucleus, removes non-coding sections (introns) from mRNA ...

Spliceosomes are large and dynamic RNA-protein complexes. The major spliceosome consists of five subunits, U1, U2, U4, U6, and U5 small nuclear ribonucleoprotein particles (snRNPs, read "snurps ...

They succeeded once they were able to isolate the splicing complexes of the fungus that were in the midst of quality control ...

Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger RNA – a prerequisite for ...

On the other hand, this protein is part of the spliceosome, a molecular complex that modifies RNA before it is translated into proteins. Dikaya and her colleagues also identified several genes ...

Then the RNA binding protein communicates to the splicing machinery to include or not include the exon into the mRNA,” Cooper explained. The fit between a splice site and the spliceosome components ...

Plants survive cold by adjusting at cellular level. Scientists discovered that the PORCUPINE protein helps plants adapt to ...

Figure 3: Nuclear protein phosphatases in spliceosome assembly and catalysis. Figure 4: The phosphorylation state of the C-terminal domain of RNA polymerase II controls transcript maturation.

Rgenta Therapeutics, a clinical-stage biotechnology company pioneering the development of a new class of oral small molecules ...

The scientists discovered that a total of 159 different protein kinases—around a third ... insulin influences the function of the so-called spliceosome complex, a key regulatory element of ...