In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
AZoLifeSciences on MSN6h
Understanding the Complex Architecture of the Minor SpliceosomeIn human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
The spliceosome then converts them into mature, functional mRNA. To do this, this large protein-RNA complex, which is located in the cell nucleus, removes non-coding sections (introns) from mRNA ...
A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is a ...
Then the RNA binding protein communicates to the splicing machinery to include or not include the exon into the mRNA,” Cooper explained. The fit between a splice site and the spliceosome components ...
Surprisingly, when spliceosome components were depleted or inhibited pharmacologically ... of canonical pre-mRNA processing events shifts the steady-state output of protein-coding genes towards ...
The spliceosome then converts them into mature, functional mRNA. To do this, this large protein-RNA complex, which is located in the cell nucleus, removes non-coding sections (introns) from mRNA ...
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