I was curious if RNA binding was a general ... mechanisms called cleavage and polyadenylation and altering mRNA after ...
Then an enzyme called poly-A polymerase adds a chain of adenine nucleotides to the RNA. This process, called polyadenylation, adds a poly-A tail that is between 100 and 250 residues long.
The realization that most human genes generate multiple mRNAs encoding divergent protein isoforms via alternative splicing and polyadenylation has revealed extensive regulation that remains to be ...
RNA-binding proteins recognize ... mRNA — is just one of many stages in the process of gene expression that can be regulated. From splicing and polyadenylation, through mRNA export to ...
Content More than 95 percent of human genes undergo alternative splicing and >50 percent of genes use alternative polyadenylation sites. For many genes, pre-mRNA processing directs expression of ...
“The actual product itself got moved a lot faster than the ecosystem around it, which is now in the process of catching ... sequencing to analyze aspects of DNA and RNA biology, including gene ...
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