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Then an enzyme called poly-A polymerase adds a chain of adenine nucleotides to the RNA. This process, called polyadenylation, adds a poly-A tail that is between 100 and 250 residues long.
Yet, sometimes 3'-end processing factors start polyadenylation earlier in the transcript ... empower scientists mapping the RNome and advance our overallunderstanding of RNA. Tecan Group (SIX Swiss ...
Content More than 95 percent of human genes undergo alternative splicing and >50 percent of genes use alternative polyadenylation sites. For many genes, pre-mRNA processing directs expression of ...
I was curious if RNA binding was a general ... mechanisms called cleavage and polyadenylation and altering mRNA after transcription via enzymes through a process called m6A modification.
The realization that most human genes generate multiple mRNAs encoding divergent protein isoforms via alternative splicing and polyadenylation has revealed extensive regulation that remains to be ...