M. tuberculosis, the etiological agent of TB is one of the most effective human pathogens and is responsible for 2.2 million deaths every year (1 death every 10 seconds). It is estimated that a total ...

However, how Mtb manipulates host molecular switches of cell death pathways to reprogram cell death modalities and drive tuberculosis pathogenesis remains poorly understood. In a study published ...

Much of the research on tuberculosis centers on its pathophysiology -- the mechanisms by which the bacteria take over and infect a host -- as well as ways to diagnose and treat the disease. For their ...

So far, much of the research on tuberculosis centers on its pathophysiology—the mechanisms the bacteria use to infect a host — as well as ways to diagnose and treat the disease. “There is a blind spot ...

IC31 did not reduce the risk of recurrent disease in individuals who completed treatment for pulmonary tuberculosis.

We are broadly interested in the biology of mycobacteria, which include the major human pathogen M. tuberculosis, the nonpathogenic model organism M. smegmatis, and the cancer biotherapeutic agent BCG ...