The selective failure of intrinsic-factor secretion in the presence of continued acid secretion is of particular interest in view of the recent observation that human parietal cells apparently ...

Parietal cells are present in the gastric pits that mainly occur in the upper part of the stomach, ... Serotonin is involved in regulating gastrointestinal motility and fluid secretion. P/D1 cells ...

In the stomach, so-called parietal cells are responsible for acid production. They react not only to the body's own messenger molecules, but also to bitter-tasting food constituents such as caffeine.

Using single-cell RNA sequencing, a technique to identify the genes expressed by a cell, the team identified what genes the cells were turning on or off as they became more mature PCs.

Gastrin released from antral G cells is generally viewed as the major physiologic regulator of gastric acid secretion and growth via the gastrin/cholecystokinin-2 (CCK-2) receptor. 6 ...

Colin Howden, MD, discusses the mechanisms at work in vonoprazan as well as patient monitoring and potential future uses following a recent FDA approval for the treatment of erosive esophagitis.