We present data from 1995, 2000, and 2005 in seven U.S. states, examining how case mix, outcome, and resource use for pediatric severe sepsis have changed over time. Conclusions: Between 1995 and ...

Neonatal sepsis is a major cause of morbidity and mortality in preterm infants. Clinical diagnosis is difficult and no reliable diagnostic test exists. Interleukin-6 (IL-6) is a central mediator ...