The answer lies in regulating the operon. As trp levels increase ... For example, specific sequences in DNA serve as binding sites for specific proteins that modulate the binding of RNA polymerase ...
He wanted the DNA to contain the genetic information encoding most of the functions of SV40, all of the functions of the E. coli galactose (gal) operon, and the minimal parts of bacteriophage lambda ...
Attenuation, or dampening, of the trp operon is made possible by the fact ... polymerase can lead to dissolution of the RNA polymerase/DNA complex (Gusarov & Nudler, 1999; Yarnell & Roberts ...
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