The more recently solved 3D structures of the PCAF and CBP bromodomains bound to lysine-acetylated histone H3 and H4 peptides provide important new insights into the structural and molecular bases ...

These incisive chemical probes have availed new insights into chromatin structure and function, and suggest plausible translational opportunities for the targeted development of drug-like derivatives ...

Although the latter portion of lysine biosynthesis, the conversion of α-aminoadipate (AAA) to lysine, in Thermus thermophilus is similar to the latter portion of arginine biosynthesis, enzymes ...

The most recently discovered amino acid, pyrrolysine, is produced by a series of just three chemical reactions with a single precursor -- the amino acid lysine, according to new research.

New research in yeast cells may have pinpointed a key enzyme in the molecular circuitry that silences genes. ... By methylating H3 at lysine 4, Set7 makes the chromatin structure more open, ...

Molecular dynamics computations reveal how histone-tail acetylation may promote or suppress gene expression. genprowebdirectory Facebook Linkedin RSS Twitter Youtube ...

Dr. Aurora Clark, a professor of chemistry at Washington State University, has worked with her students to create a unique program called moleculaRnetworks, which actually takes the PageRank ...

Researchers from Osaka University have found that the attachment of a ubiquitin molecule to a protein called PCNA at the lysine 107 position causes gross chromosomal rearrangements. This lysine ...