In most eukaryotic cells, two types of spliceosome work in parallel to stitch gene pieces together: the major spliceosome and the minor spliceosome. The Galej Group at EMBL Grenoble has published ...

In most eukaryotic cells, two types of spliceosome work in parallel to stitch gene pieces together: the major spliceosome and the minor spliceosome. The Galej Group at EMBL Grenoble has recently ...

In most eukaryotic cells, two types of spliceosome work in parallel to stitch gene pieces together: the major spliceosome and the minor spliceosome. The Galej Group at EMBL Grenoble has recently ...

“However, analyzing the components flexibly bound to the periphery of the spliceosome was a major challenge for our work,” explains Dr Komal Soni from the BZH. Based on this structural ...

The vast majority of introns are removed by the major spliceosome, a 60 S complex containing five small nuclear RNAs (snRNAs: U1, U2, U4, U5 and U6) and well over 50 different polypeptides (Fig.