RNA repair enzymes capable of sealing 2’,3’-cyclic-PO 4 /5’-OH breaks or 3’-OH/5’-PO 4 breaks are present in diverse taxa in all phylogenetic domains of life. ATP-dependent RNA ligases join 3’-OH and ...
“Using our new ligase enzymes we can produce peptides with promising anti-cancer activity in a single process with excellent yields. Previously, these types of peptides were produced in much lower ...
The DNA repair and replication pathways converge on a common final step in which the continuity of the repaired DNA strand is restored by DNA ligase, an enzyme that converts nicks into phosphodiester ...
Digestive enzymes, for instance, belong to the hydrolase category and help break down foods to make them more easily absorbed throughout the body. There's also metabolic enzymes, which belong to the ...
Scientists use them to cut DNA molecules at interesting specific locations and then reattach different DNA sequences to each other using an enzyme called DNA ligase, creating new, recombined DNA ...
During ubiquitination, a group of enzymes called E3 ubiquitin ligases attach a small protein called ubiquitin to other proteins. This tagging, in turn, helps determine the fate of the targeted ...