To circumvent this problem, we also analyzed single-intron exon 4 constructs, in which only intron-defined spliceosome assembly can occur and no alternative splicing pattern is possible .

This spliceosome is made up of variety of protein and RNA components, and for each splicing process, it is reassembled at the sites where an exon joins an intron and the intron in turn connects to ...

This spliceosome is made up of variety of protein and RNA components, and for each splicing process, it is reassembled at the sites where an exon joins an intron and the intron in turn connects to ...

This spliceosome is made up of variety of protein and RNA components, and for each splicing process, it is reassembled at the sites where an exon joins an intron and the intron in turn connects to ...

As DNA is transcribed into RNA it needs to be edited to remove non-coding regions, or introns, shown in green. This editing process is called splicing, which involves removing the introns, leaving ...

General mechanism of intron recognition during spliceosome assembly The structure of a cross-exon spliceosome stalled by SSA captures the intron recognition by U2 snRNP. This indicates that early ...

The structure of a cross-exon spliceosome stalled by SSA captures the intron recognition by U2 snRNP. This indicates that early prespliceosomes (E complexes) select introns through a toehold-mediated ...

In this study, the researchers reveal the structure of U11 snRNP—one of the five subunits of the minor spliceosome, which initiates the intron selection process. Stitching gene pieces together.

In this new study, the researchers reveal the structure of U11 snRNP – one of the five subunits of the minor spliceosome, which initiates the intron selection process. Stitching gene pieces together ...

In this new study, the researchers reveal the structure of U11 snRNP -- one of the five subunits of the minor spliceosome, which initiates the intron selection process. Stitching gene pieces together ...