Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...

splicing itself must be quite ancient. Proponents of the "intron-early" theory suggest that all organisms (including prokaryotes) at one time had introns in their genome but subsequently lost ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

Alternative splicing promotes adaptation to environmental changes; in fungi, the most common example of alternative splicing is intron retention. To explore the relationship between splicing and ...

Alternative splicing (AS), a critical process for gene expression regulation, allows a single precursor RNA to produce multiple transcript variants. Alterations in exon exclusion, intron retention ...

Boehringer will leverage ExpressionEdits' Genetic Syntax Engine which generates optimized introns to increase protein expression.

Fungal tRNA Splicing as a Paradigm of RNA Repair – Intron-containing tRNAs are widespread in eukarya; the intron is usually located in the anticodon loop of the pre-tRNA and must be removed precisely ...

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