A critical finding regarding the prevalence of alternative splicing was that a majority of human genes produce a wide variety of messenger RNAs (mRNA) that in turn encode distinct proteins ...

which appears to influence the expression of about half of all human genes, is found throughout the animal kingdom, as well as in plants. The findings suggest that the control of RNA splicing, a ...

Like a complex library in a tiny space 50 times smaller than the width of a human hair ... transcribed genes are in close proximity to speckles, enabling more efficient splicing.

Content More than 95 percent of human genes undergo alternative splicing and >50 percent of genes use alternative polyadenylation sites. For many genes, pre-mRNA processing directs expression of ...

The lab of Dan Xu, PhD, assistant professor at The Hormel Institute, has published a groundbreaking study in Cell Metabolism, a highly prestigious scientific journal. The paper, entitled "Isoform ...

In a study published in mBio, a research team identified alternative splicing—the selective inclusion or excision of introns in a gene—as a contributor to filament formation in fever-like temperatures ...

which appears to influence the expression of about half of all human genes, is found throughout the animal kingdom, as well as in plants. The findings suggest that the control of RNA splicing, a ...

A new contender for a human 'language gene' can change the way that mice squeak when it is incorporated into their DNA.

The realization that most human genes generate multiple mRNAs encoding divergent protein isoforms via alternative splicing and polyadenylation has revealed extensive regulation that remains to be ...