The hammerhead ribozyme is a self-cleaving molecule that essentially cuts itself in two. This self-cleaving action in the messenger RNAs effectively turns off the genes by preventing protein ...

The hammerhead ribozyme is a self-cleaving molecule that essentially cuts itself in two. This self-cleaving action in the messenger RNAs effectively turns off the genes by preventing protein ...

The hammerhead ribozyme is a more efficient ribonuclease than an RNA ligase. Under typical reaction conditions, the rate of RNA chain cleavage is ∼100-fold faster than the rate of the reverse ...

A novel class of potent hammerhead inhibitors is represented by two dye molecules that have not yet been shown to affect ribozyme catalysis, namely bisbenzimide (Hoechst 33258), and the bis-N ...

The hammerhead ribozyme has been the subject of intensive investigations by researchers around the world, and Scott found his most cherished accomplishments called into question. "In 2002, I had ...

Wochner and her colleagues were able to use tC19Z to synthesize a minimal version of the hammerhead ribozyme (an RNA that binds to and cleaves an RNA substrate).

In the new experiment, researchers built their logic gates using a type of catalytic RNA called a "hammerhead ribozyme." Image: UCSB chemistry.

Atomic-resolution structure of a ribozyme yields insights into RNA catalysis and the origins of life. Which came first, nucleic acids or proteins?

The scientists started with a hammerhead ribozyme called N107 that had been used as an RNA switch in prior studies, but they found that the difference in production of a transgene-encoded test protein ...

image: An RNA ligase ribozyme assembled from three RNA strands, ... The evolution involved synthesis of a specific hammerhead ribozyme structure, ...

The hammerhead ribozyme is a self-cleaving molecule that essentially cuts itself in two. This self-cleaving action in the messenger RNAs effectively turns off the genes by preventing protein ...