Post-mortem examination of a mouse heart shows a clear delineation in blue where TREE gene enhancer sensed and responded to tissue damage of a heart attack. photo - Ken Poss Lab, Duke University ...

Researchers used powerful technology to analyse thousands of individual cells at once, considering which genes are active.

Although these non-coding regions do not encode proteins, they contain regulatory elements such as enhancer sequences, which play crucial roles in controlling gene expression. Enhancers can ...

An international collaboration of researchers led by Masahito Yoshihara at Chiba University (Japan) has identified novel transcriptional enhancers that regulate gene expression in neuronal development ...

Two other groups had previously used CRISPR to create knockout libraries of protein-coding genes in human cells for functional genetic screens. But the current work is the first genetic screen of ...

RNA polymerase binds to a region just before the gene, called the promoter, before moving down the DNA to the gene. Enhancers are regions of DNA that act as molecular switches for turning genes on or ...

In a 2010 Nature paper, researchers in the lab of neurobiologist Michael Greenberg at Harvard Medical School reported that enhancers can produce RNA. Working with cultured mouse neurons, the ...

Enhancer Biology lab studies gene regulation and genome architecture controlled by transcription factors using genome-wide functional genomics methods. Our aim is to understand enhancer malfunction ...