The first step in transcription is initiation, when the RNA pol binds to the DNA upstream (5′) of the gene at a specialized sequence called a promoter (Figure 2a). In bacteria, promoters are ...

Research scientists have managed to sequence DNA transcription initiation "image by image" to show how DNA is copied onto RNA. Some of the mechanisms of this crucial stage have now been revealed.

Scientists at St. Jude Children's Research Hospital have reconciled two closely related but contentious mechanisms underlying transcription, the process of converting genetic information in DNA into ...

Transcription factors can increase and decrease gene expression, and sometimes work with protein partners to do so; they tend to have an end that can bind to DNA and another end that can attach to ...

Accurate measurement of DNA or RNA concentration and purity is fundamental for many downstream processes, including transfection, electroporation, cloning, PCR and NGS. 1, 2 Without proper ...

DNA and RNA methylation, initially thought to operate as distinct pathways, have been shown to interact closely, shifting our understanding of gene regulation. A team of researchers from the ...

Dr. Young and lead authors Ozgur Oksuz, Ph.D., and Jonathan E. Henninger, Ph.D., and colleagues discovered that at least half of the approximately 1,600 TFs in the human genome also bind to RNA.

image: DNA transcription is a crucial process in the expression of genetic information, as it converts the information stored in DNA into messenger RNA, which can then be translated into proteins.

RNA transcription is the genomic process in which a cell produces a duplicate of a gene’s DNA sequence. In a study published in Nucleic Acids Research, University of Alabama at Birmingham Department ...