More information: Zhiyuan Xie et al, DNA-guided transcription factor interactions extend human gene regulatory code, Nature (2025). DOI: 10.1038/s41586-025-08844-z Provided by Wellcome Trust ...

A cold sore might seem like a minor nuisance. But behind that tingling lip is one of the world’s most widespread and cunning ...

This study has shown that HSV-1 is an "opportunistic interior designer" of human cells. | Genetics And Genomics ...

Researchers discovered that HSV-1 (herpes simplex virus) actively reshapes the 3D layout of human DNA within hours of ...

Viruses are entirely dependent on their hosts to reproduce. They ransack living cells for parts and energy and hijack the ...

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can ...

image: DNA transcription is a crucial process in the expression of genetic information, as it converts the information stored in DNA into messenger RNA, which can then be translated into proteins.

Every day, our bodies perform around 330 billion cell divisions to keep us alive and functioning. These divisions rely on the ...

S enescent cells, those that persist in the body despite having halted cell division, undergo a process called cryptic transcription, whereby they produce RNA transcripts from short sequences nested ...

DNA study reveals modern humans evolved from two ancient groups ... By opening up tightly packed regions of DNA, TEs allow the machinery of transcription to reach the genes that need to be turned on.

Mitochondrial deoxyribonucleic acid (mtDNA) plays a crucial role in energy production and abnormalities in mtDNA are linked to various diseases. However, its regulatory mechanism remains ...

Now biologists have discovered that it happens early—in fact, human sperm's few mitochondria contain virtually no DNA at all. The findings were published in a recent issue of Nature Genetics .