Chromatin refers to proteins that help organize ... James Watson and Francis Crick were able to piece together the first accurate model of DNA. Shown here is the structure of naked DNA -- DNA ...

The AI model that they designed can quickly analyze DNA sequences and predict the chromatin structures that those sequences might produce in a cell. "Deep learning is really good at pattern ...

Around the same time, researchers James Watson and Francis Crick were pursuing a definitive model for the stable ... in a coiled form is called chromatin. DNA can be further compressed through ...

A physically consistent and realistic structural model for DNA organization in chromosomes ... and the known self-associative ...

the DNA might, for example, spiral through a centromeric higher-order structure. Flanking heterochromatin might form a boundary that limits the spreading of centromeric chromatin in monocentric ...

In their new study, the researchers examined the spatial organization of chromatin, which includes DNA and related structural proteins, in one of the most interesting model organisms in biology ...

To do so, they planned to stabilize proteins at their chromatin binding locations and use nucleic acid hybridization to fish out specific DNA sequences along with the bound proteins. By using enzymes ...

“We proposed that dehydration led to a glass transition of chromatin that arrested molecular movement of DNA fragments, which we dubbed chromatin glass, or ‘chromoglass’.” The researchers tested a ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...