More information: Cristian Prieto-Garcia et al, Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy, Science (2024). DOI: 10.1126/science.adi5295 ...

The remaining 209 clusters (186 genes) had unequivocal alternative splicing events, with cryptic exons, 5′ exon extensions and 3′ exon extensions occurring in roughly equal proportions.

1129–5923C>G) that affects pre-mRNA splicing and is in complete linkage with the more frequent of the two associated haplotypes (hapB3) (Table 1). [43] This variant creates a cryptic splice ...