In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive ...

For example, many types of RNA have been found to be catalytic--that is, they carry out biochemical reactions just like enzymes do. Furthermore, many other varieties of RNA have been found to have ...

In fact, rRNA is sometimes called a ribozyme or catalytic RNA to reflect this function. Eukaryotic and prokaryotic ribosomes are different from each other as a result of divergent evolution.

Studies suggest that naturally occurring SAM-binding RNA could be derived from earlier ribozymes that lost their catalytic function during evolution," says Höbartner. Knowledge of the structure ...

Our laboratory carried out research in two areas. In one, we studied the structure and mechanism of activity of the catalytic RNA moiety of the RNA processing enzyme ribo-nuclease P (Rnase P). In the ...

We are interested in the chemistry and biochemistry of DNA and RNA, with special regard to novel structural and functional properties for these nucleic acids. Two major areas of interest are: (1) New ...

This discovery led to the concept of the ribosome as a ribozyme, an RNA molecule with enzymatic properties. The catalytic center of the ribosome, known as the peptidyl transferase center (PTC), is ...

Some RNA molecules, called ribozymes, possess catalytic activity and can catalyze chemical reactions. For example, the ribosome itself is a ribozyme, as the rRNA component catalyzes the formation of ...

We are also exploring novel methods for the detection of residual dipolar couplings (RDCs) which assist in determining the correct global structure of an RNA. Ribozymes are catalytic RNAs that perform ...

I am interested in the chemistry and biochemistry of DNA and RNA, with special regard to novel structural and functional properties for these nucleic acids. Two major areas of interest are: New ...