2010;30(2):147-159. Taken together, many drugs as well as endogenous steroid metabolites have the potential to interfere with transport activity of BSEP. As this includes direct and indirect ...
At early-stage cholestasis, most canalicular transporters and sinusoidal uptake transporters were downregulated, including bile salt export pump (BSEP, ABCB11), multidrug resistant protein 3 (MDR3 ...
[1] The discoveries that mutations in several bile export pumps (MDR3, BSEP) result in progressive familial intrahepatic cholestasis have provided dramatic proof of the important role that these ...
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