Cholestatic pruritus is a common symptom of primary biliary cholangitis (PBC), a rare autoimmune liver disease. Researchers are looking to establish the safety and efficacy of linerixibat – an ...

In the early stages of primary biliary cholangitis, symptoms occur gradually. The most common initial signs are a feeling of chronic fatigue and pruritus (itchy skin). As primary biliary ...

Explore the causes of itching in liver diseases and tips to relieve discomfort. Learn about treatments for pruritus and when ...

culminating in immune-mediated damage to the biliary epithelial cells. Predominantly afflicting middle-aged women, PBC manifests most commonly through fatigue and pruritus. Diagnostic laboratory ...

GSK has reported promising results with a drug to treat the severe itching that plagues patients with rare cholestatic liver disease primary biliary cholangitis (PBC). Interim results from the ...

Patients with PBC not only have severe liver disease and progression but also suffer from significant symptom burden—namely pruritus ... living with primary biliary cholangitis (PBC).” ...

The most common symptoms of PBC are pruritus (chronic itch) and fatigue, which can be debilitating for some people. There is currently no cure for PBC and treatment goals include slowing disease ...

Biliary tract cancer is a rare adenocarcinoma that occurs in a bile duct, often causing jaundice, pruritus and weight loss. The lesion may be papillary or flat and ulcerated. The tumour is often ...

Pruritus is a common symptom that can significantly ... U.S. Indication for Livdelzi Livdelzi is indicated for the treatment of primary biliary cholangitis (PBC) in combination with ...