“A truncated protein might cause a lot of problems … Nonsense mediated decay is a mechanism to get rid of that RNA before it's translated into a protein.” Alternative splicing plays a pivotal role in ...

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Alternative splicing (AS), a ...

Specific RNA Sequences Are Required for Regulation of Alternative Splicing If we want to understand the splice code, then we need to analyze the existing information about constitutive and ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

In this webinar, Dr. Megan L Noonan will present her research on the role of alternative splicing in kidney disease progression, discussing how she used nanopore RNA sequencing to accurately detect ...

Working at the interface of RNA splicing and breast cancer biology, our current focus is on regulation of breast cancer metastasis driven by alternative splicing. We use molecular biology, genomics, ...

Biogen has been involved in RNA splicing research since its earliest ... The antisense oligonucleotide works by modulating alternative splicing of the SMN2 exon which is mutated in the disease.

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...

and sites of RNA methylation, to mention a few. It is now clear that regulation of alternative splicing has a huge impact on gene function and there is a great deal to learn about questions ranging ...