Jamie-Lynn Sigler and Robert Iler, who played siblings Meadow and A.J. Soprano, respectively, face off in PEOPLE's exclusive ...

Christina Applegate and Jamie-Lynn Sigler share painful MS experiences on MesSy podcast, offering support and advice for ...

Christina Applegate is shedding more light on her battle with multiple sclerosis. “For three years, since I was diagnosed, ...

Christina Applegate is letting fans in on some of the details of her struggle against MS over the past three years.

Christina Applegate revealed in a new episode of her podcast that she has been hospitalized "upwards of 30 times" due to MS ...

The "Dead to Me" star shared the toll that multiple sclerosis has taken on her body and digestive system since she was ...

Christina Applegate shared a health update on her multiple sclerosis battle, revealing she's been hospitalized over 30 times ...

The actress says the autoimmune disease has caused major digestive issues affecting her gastrointestinal system and resulting ...

Christina Applegate revealed she's been hospitalized more than 30 times in three years since being diagnosed with multiple ...

Jamie-Lynn Sigler is going up against her Sopranos brother, Robert Iler, on The $100,000 Pyramid! In PEOPLE's exclusive look at the March 23 episode of the game show, the two former costars ...

Christina Applegate says that she’s been in the hospital ‘upwards of 30 times’ because of diarrhea and vomiting ...