The San Francisco 49ers may have two new starting safeties in Week 1 this season after a free agent loss and an injury to a starter.

Re-signings, contract extensions, free agent acquisitions, tendered contracts, player exits, retirements and releases - there have been a multitude of changes to the San Francisco 49ers roster ...

Brandon Aiyuk's ACL tear affects the 49ers' season, adding to difficulties from other injuries and roster changes. Ben and Donnie discuss his timeline.

The 49ers’ active roster will change on Wednesday, and it will continue to be tweaked as players are injured or upgrades are available to be added. Advertisement. Advertisement.

Another San Francisco 49ers preseason game is in the books. They knocked off the New Orleans Saints 16-10 at Levi's Stadium on Sunday. That means it's time for a new 53-man roster projection, and ...

Here are your top 49ers storylines for Thursday, September 15th. Mack (6-0, 212) was originally drafted by the Indianapolis Colts in the fourth round (143rd overall) of the 2017 NFL Draft ...

The 49ers announced a flurry of staff changes this week. ... Hampton is primarily focused on the 49ers’ roster construction and contract negotiations, particularly relating to the salary cap.

Last season, the 49ers chose to run it back by doubling down on proven but aging and fragile veterans, who predictably fell to injury. Running it back in 2025 risks the same result. Changes are ...

Another San Francisco 49ers preseason game is in the books. They knocked off the New Orleans Saints 16-10 at Levi's Stadium on Sunday. That means it's time for a new 53-man roster projection, and ...

That's why the 49ers' biggest storyline heading into camp this year, according to ESPN, is whether the 49ers will return to ...